WebAug 29, 2024 · Purpose The extracellular domain (ECD) of human epidermal growth factor receptor-2 (HER2) in the blood is a promising biomarker of cancer prognosis and … WebMay 20, 2011 · Piezoelectric microcantilever sensors (PEMS) can be sensitive tools for the detection of proteins and cells in biological fluids. However, currently available PEMS can only be used a single time or must be completely stripped and refunctionalized prior to subsequent uses. Here we report the successful use of an alternative regeneration …
10.1016/j.ctrv.2011.03.008 DeepDyve
WebApr 5, 2016 · The molecular weight of the sHER2 fragments were compared with the band of recombinant human HER2-ECD, and with the bands detected in whole cell extracts of … WebJan 7, 2024 · During HER2-positive breast cancer progression, tumor cells shed the extracellular domain (ECD) of HER2 by proteolytic cleavage , and this shedding is reported … barnegat nj weather 10 day
Challenges in detection of serum oncoprotein BCTT
WebJul 15, 2010 · Transfectants releasing high levels of 110-kDa rECD, identical in size to native HER2/ECD (nECD), grew significantly slower than did controls, which constitutively released only basal levels of nECD. While transmembrane HER2 and HER1 were expressed at equal levels by both controls and transfected cells, activation of these molecules and of … WebWork by Peiris et al and others have demonstrated that the HER2 ECD is variably glycosylated depending on oncogenic status and epitope masking due to heavy … WebJul 5, 2024 · 虽然sher2 ecd阳性不能替代ther2组织阳性指导临床诊疗,但一些研究发现sher2 ecd水平与ther2状态、疾病分期和无病生存时间存在有一定关系。 多因素分析表明sHER2 … barnegat nj to manahawkin nj