Web51 rows · Vesicant: Medication that may causes severe and/or irreversible tissue injury and necrosis. Irritant: Medication that can cause local inflammatory reactions at the infusion site, which may include: burning, swelling, pain, inflammation, tightness, or phlebitis. Clinical … Webmay rarely cause local tissue necrosis, leading to the suggestion that paclitaxel may have vesicant properties. In some reports, patients have experienced recall reactions from previous paclitaxel extravasations. No correlation has been made between concentration or volume of paclitaxel extravasated and the risk of tissue necrosis.
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WebAug 31, 2015 · Nab- paclitaxel ( Abraxane) is a taxane -type chemotherapy medicine used to treat breast cancer. It is paclitaxel ( Taxol) wrapped in the protein albumin. The albumin allows the medicine to be given in water. This lessens the risk of an allergic reaction, which is common with taxanes like paclitaxel or docetaxel. WebJul 16, 2024 · • Vesicant. Dextrose in Water • Central line is preferred for infusion concentrations ≥10%. Preference for administration via central line: Some medications when administered peripherally may cause soft tissue irritation, inflammation, and potential necrosis may occur with extravasation or infiltration of vesicants and irritants. mysql txtファイル
Severe necrosis due to paclitaxel extravasation - PubMed
WebNov 6, 2013 · Extravasation of a vesicant is a potentially disfiguring event associated with many commonly used intravenous antineoplastics. Some chemotherapeutic agents, such … WebJan 1, 2024 · Paclitaxel, USP is a white to off-white crystalline powder with the empirical formula C 47 H 51 NO 14 and a molecular weight of 853.9. It is highly lipophilic, insoluble in water, and melts at around 216° to 217°C. … WebChemotherapeutics can be classified into three categories: vesicants, irritants, and non-irritants. Vesicants can cause pain, edema, and erythema, and potentially lead to blisters and tissue necrosis when … mysql sqlexception エラーコード 一覧