WebProduct name Nigericin Na+ salt, K+ ionophore Description K + ionophore Biological description K + ionophore; exchanges K + for H + across most biological membranes. … Web21 okt. 2024 · Nigericin, another mobile carrier, left both isoforms unaffected. The membrane-integral pore-forming gramicidin evenly inhibited TbAQP2 and TbAQP2 in the …
Intracellular pH Modulates Autophagy and Mitophagy
WebWell-known ionophore-antibiotics include Valinomycin, Gramicidin, Nigericin, Monensin and Monactin, which kill cells by altering ionic gradients. Valinomycin specifically transports potassium while others transports monovalent cations such as sodium, potassium, hydrogen and ammonium ions. Web25 sep. 2024 · Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei parasites. The T. brucei aquaglyceroporin isoform 2, TbAQP2, has been linked to the uptake of pentamidine. Negative membrane potentials and transmembrane pH gradients were suggested to promote transport of the dicationic antitrypanosomal drug. Application of … how many schizophrenics are homeless
Nigericin-induced Na+/H+ and K+/H+ exchange in synaptosomes …
WebNigericin sodium salt acts as a potassium ionophore. It probably activates NLRP3 through the intracellular potassium (K+) efflux across the membrane [1]. Whether the formation of non‑selective pannexin-1 pores also contributes to NLRP3 activation upon … Inflammasome activation with Nano-SiO 2. NLRP3 Inflammasome Inducer - Silicon … Inflammasome activation with Hemozoin crystals. NLRP3 Inflammasome Inducer … Inflammasome activation with Alum. NLRP3 Inflammasome Inducer - Alum … Needle is a component of the type III secretion systems (T3SS) of intracellular … Rod is a component of the type III secretion systems (T3SS) of intracellular bacteria … Purified Flagellin from Pseudomonas aeruginosa.FLA-PA, a ~52 kDa protein, … Inflammasome activation with CPPD crystals. NLRP3 Inflammasome Inducer … Mincle Agonist - Synthetic analog of the cord factor. Trehalose-6,6-dibehenate … WebNigericin is a carboxylic ionophore that exchanges K + (and to a lesser extent Na +) for H + across cell membranes. If one is successful in choosing [K +] o to match [K +] i, then … Web12 okt. 2015 · Nigericin, a K +,H +-ionophore 1-21 with antibiotic 10, 22-26, antimalarial 27, anti-Toxoplasma gondii 28 and antiviral 11, 29, 30 potency, has been considered for … how did babe ruth influence baseball